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Central activities of hydroalcoholic extract from Lafoensia pacari A. St.-Hil. stem bark BJPS
Galdino,Pablinny Moreira; Nascimento,Marcus Vinícius Mariano; Sousa,Fábio Borges de; Ferreira,Reginaldo Nassar; Paula,José Realino de; Costa,Elson Alves.
Lafoensia pacari A. St.-Hil. can be found from Amapá to Rio Grande do Sul states, and also in Paraguay and Bolivia. It is popularly known as pacari or mangava-brava and is used to promote weight loss, as an anti-thermal or tonic, to treat gastritis, ulcers, scarring, itching, discouragement, and cancer. In the open field tests, the hydroalcoholic extract from L. pacari stem bark (HEP) decreased the number of rearings, number of invaded squares, and increased immobility time compared to control animals. In the pentobarbital-induced sleep time test, HEP decreased latency time to sleep and increased sleeping time. In the rota-rod test, no changes in the studied parameters were observed. In the elevated plus maze, HEP increased the percentage time and...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Lafoensia pacari A. St.-Hil/pharmacognosy; Hydroalcoholic extract; Central Nervous System/experimental study; Anxiety/experimental study.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000300008
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Evaluation of the antinociceptive and anti-inflammatory effects of the acetone extract from Anacardium occidentale L BJPS
Vanderlinde,Frederico Argollo; Landim,Higor Frutuoso; Costa,Elson Alves; Galdino,Pablinny Moreira; Maciel,Maria Aparecida Medeiros; Anjos,Gineide Conceição dos; Malvar,David do Carmo; Côrtes,Wellington da Silva; Rocha,Fábio Fagundes da.
The stem bark of Anacardium occidentale L. (Anacardiaceae), commonly called cashew, is used in Brazilian traditional medicine for the treatment of gastric and inflammatory disorders. The present study was carried out to investigate the in vivo anti-inflammatory activities of the acetone extract (AE) of the stem bark of A. occidentale. We evaluated the pharmacological activities of this plant material through the analgesic, antiedematogenic and chemotaxic inhibitory effects produced by the AE. The oral administration (p.o.) of mice with the AE (0.1, 0.3 and 1.0 g/kg) or positive control indomethacin (10 mg/kg) inhibited acetic acid-induced writhing by 18.9, 35.9, 62.9 and 68.9%, respectively (ID50% = 530 mg/kg). The highest dose of the AE was able to...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Anacardium occidentale L./analgesic activity; Anacardium occidentale L./anti-inflammatory activity; Anacardium occidentale L./antiedematogenic activity; Anacardiaceae; Cashew.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502009000300008
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